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People taking metformin alongside tirzepatide for diabetes management are at increased risk of B12 deficiency because metformin impairs B12 absorption

This means the FDA has not reviewed them for safety, effectiveness, or quality

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As a compound moves toward higher levels in any research design, monitoring tends to become more frequent, not less, since the goal is to catch any emerging safety signal as early as possible

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Rybelsus and Wegovy ) than once-weekly semaglutide