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Preclinical investigations have yielded significant understanding of the processes and thresholds of lipid peroxidation in cancer treatment, with agents such as sorafenib and RSL3 demonstrating effectiveness in preclinical models of therapy-resistant malignancies [240]

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Larsson A, Mattsson B, Wauters EA, van Gool JD, Duran M, Wadman SK: 5-oxoprolinuria due to hereditary 5-oxoprolinase deficiency in two brothers--a new inborn error of the gamma-glutamyl cycle