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Additionally, oxidative stress significantly impairs RFC function: Low glutathione: Reduces RFC function ~20-40% High nitric oxide: Reduces RFC function ~35% Hyperglycemia: Reduces RFC function ~20-35% Even if you're taking Leucovorin, oxidative stress can prevent it from reaching your brain

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Magnesium aids in improving brain function by supporting the nervous system, enhancing sleep quality, reducing inflammation, and reducing stress levelsall factors that can mitigate the symptoms of brain fog