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Interleukin-1 beta and interleukin-6 are elevated in the cerebrospinal fluid of Alzheimer's and de novo Parkinson's disease patients

Vitamin E supplementation has been shown to improve insulin action

Obese mice and rats treated with AOD9604 showed significant decreases in adipose tissue depot weights, reductions in adipocyte size observed histologically, and improvements in body composition measured by DEXA scanning or MRI

This is an area of ongoing research, and patients with a history of depression should discuss monitoring strategies with their provider

Both DAPA-CKD and EMPA-KIDNEY demonstrated substantial kidney protection irrespective of diabetes status

Most practitioners and longevity doctors do not use a multiomics lens