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Briefly, islets were handpicked, transferred to a petri dish containing 11 mL of KrebsRinger bicarbonate (KRB) buffer supplemented with 0.1% bovine serum albumin (BSA) and 3 mM glucose, and incubated at 37 C and 5% CO 2 for 60 min

Extensive research is currently underway on the effects of these drugs with GLP-1RA properties in brain diseases

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Patients and clinicians are exploring these strategies because of cost, access, GI tolerability, and the challenge of maintaining long-term treatment

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