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It is administered once weekly and has become one of the most widely recognized diabetes and weight-loss medications globally

Instead, treatment increasingly aims to address metabolic dysfunction in general, including weight, cardiovascular risk and long-term organ protection

Sodium and potassium should be monitored and supplemented if necessary

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OptumRx/UHC typically requires documented failure of at least 2 oral migraine preventives such as topiramate (Topamax), propranolol, amitriptyline, or similar accepted agents due to inadequate efficacy or intolerable side effects