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doi: 10.1038/nm.3882

B12 supplementation is well-tolerated and does not add adverse effects

For individuals experiencing mild gastrointestinal upset from B12 supplements (uncommon but possible with high doses), taking the supplement with breakfast may improve tolerance

We've come to the conclusion that taking vitamin B12 in liquid form - rather than pill, or capsule- is best because the liquid is able to mix with the saliva to break away from food and allow it to bind with other proteins

Additionally, it is also used in the treatment of cyanide poisoning, a condition that can cause rapid breathing, confusion, and seizures

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