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This research shows us that they might be useful to manage food preoccupation and binge eating, but not in their current form. Halpern agreed, noting that research in this area is in its infancy

Whether used as part of an exercise program or for general health optimization, the research suggests that dihydroberberine's benefits extend well beyond its primary role as a glucose disposal agent

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Progression to metabolic dysfunction-associated steatohepatitis (MASH) with significant or advanced fibrosis (F2-F3) marks a threshold at which the risk of cirrhosis, hepatocellular carcinoma (HCC), and liver-related mortality rises sharply, and where targeted pharmacologic intervention is most likely to alter long-term prognosis [2]