[DOI] [PubMed] [Google Scholar] Zhang J, Li L
Journal reference: Gonzalez-Rellan, M
A combined effect that is bigger than just decreasing calories is thought to be at play when looking at the effects of activating the GLP-1 receptor.[ref] In overweight adults aged 45+, a 4-year-long study using semaglutide for weight loss also prevented HbA1c from rising over time, which was seen in the placebo arm
Developed by the Danish pharmaceutical company Novo Nordisk, Saxenda was approved by the FDA in December 2014 for the treatment of chronic weight management, combined with a reduced-calorie diet and physical activity
Common injection site reactions include mild redness, bruising, or temporary stinging
The gut-brain axis, increasingly recognized for its importance in mental health, may be positively influenced by GLP-1 therapies