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277 Scavenger receptor class B type I (SRBI) plays a crucial role in promoting cholesterol efflux from cells and clearing plasma cholesterol, while SRBI deficiency results in disrupted cholesterol metabolism, hyperlipidemia, and subsequent ferroptosis via the HIF-1/TFR1 pathway

However, even though alloxan did not inhibit the GLUT2 transporter function 29 , in this study, no alteration in GLUT2 levels was seen after administration of the QV formulation

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PFIC 4 patients are very rare

Under physiological conditions, the BRB coordinates vascular and extravascular systems to maintain osmotic balance, regulate ion concentrations, and facilitate nutrient/metabolite transport, thereby preserving retinal microenvironmental homeostasis