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A large systemic review of cardiovascular outcomes of people taking GLP-1 agonists significantly reduces death from cardiovascular causes by 12% and stroke by 16%

Barba, I., Carrillo-Bosch, L

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DOI: 10.1146/annurev.pharmtox.39.1.267 71

IGF-1 is a growth factor, and chronically elevated levels carry theoretical concerns about promoting the growth of pre-existing neoplasms

But using MMA levels to determine B12 status has its own complications