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Conventional delivery of antioxidants faces several challenges, including poor bioavailability, low stability, rapid clearance, short half-life, poor targeting, non-specific distribution, gastrointestinal degradation, low penetration of biological barriers, cytotoxicity, and pro-oxidant effects at high doses [31]

causes include Graves' disease (autoimmune, 60-80 percent), toxic nodular goiter (common in older adults), and thyroiditis (transient)

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This approach helps control blood sugar levels and prevent complications from diabetes, such as heart disease or kidney failure

Drawing earlier catches acute toxicity but misses steady-state dynamics

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