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Therefore, an anti-mouse GIPR surrogate antibody was used to conjugate with the GLP-1 analogue peptide to generate an AMG 133 murine surrogate to assess its effect in pharmacology studies in mice

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27 In the pancreas In pancreatic beta cells, GLP-1 RAs enhance glucose-stimulated insulin secretion by activating the GLP-1R, a G protein-coupled receptor mainly coupled with the Gs subunit

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