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This review highlights the limitations of conventional approaches and explores alternative strategies, including LT4+LT3 combination therapy, total thyroidectomy, and adjunctive treatments such as supplements, herbal medicine, and acupuncture

Data extraction and quality assessment were performed, focusing on primary outcomes, including changes in triglycerides (TG), total cholesterol (TC), high-density lipoprotein (HDL), low-density lipoprotein (LDL), and very low-density lipoprotein (VLDL), and secondary outcomes including blood pressure (BP) and body mass index (BMI)

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For researchers requiring high-certainty evidence, Tesamorelin alone is the better-supported choice

10.1016/j.psyneuen.2020.104687 108 VestlundJ.BergquistF.LicheriV.AdermarkL.JerlhagE