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Effects of DSIP: Circadian Rhythm Stabilization: Investigated for its ability to induce sleep patterns that mimic natural physiological rest without disrupting REM cycles
Sekine I, Minna JD, Nishio K, Tamura T, Saijo N (2006)
L.OtsukaH.BhushanS.WangZ.BradleyJ.TrivediR.et al (2016)
Both obesity and diabetes can lead to lung function impairment by causing chronic inflammation and delaying ineffective immune response
What they found: Mean weight loss: 2.6 kg vs 2.3 kg placebo , a difference of only 0.3 kg (1 %) Statistically non-significant Clinically unsatisfactory for the obesity indication Safety profile remained favorable Why it matters: The study stopped the development of AOD-9604 as a drug
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