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Referral to an endocrinologist is recommended for patients who are pregnant or planning pregnancy, pediatric patients, those with nodules or goiter, discordant laboratory results, persistent symptoms despite normal TSH, or suspected myxedema coma (requiring urgent care)

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7.3.2.2 In vitro model system development Current efforts to develop organoid models of human testicular tissue remain in early experimental phases, with significant technical challenges limiting their immediate applicability to EED research

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