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When GLP-1 medications are discontinued, it often leads to noticeable shifts in weight and blood sugar management
doi: 10.1007/s11947020-024287 232 GruskieneRBockuvieneASereikaiteJ
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This structural similarity near the G protein coupling sites reflects a convergence of activation pathways, which has been highlighted in family A GPCRs 43 , and enables this large family of receptors to bind and get activated by very diverse ligands, but signal intracellularly via a small common repertoire of G proteins
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