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Extending the half-life also extends the pharmacokinetic properties of liraglutide - upregulating intracellular cAMP levels via GPCR-signaling pathway in elevated blood glucose concentrations, promoting insulin release, and attenuating glucagon secretion

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[Google Scholar] 19.Jensen M.D., Ryan D.H., Apovian C.M., Ard J.D., Comuzzie A.G., Donato K.A., Hu F.B., Hubbard V.S., Jakicic J.M., Kushner R.F., et al

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