Potential risks, including viral reactivations, malignancies, and autoimmunity, must be carefully considered in conjunction with the potential benefits
Figure 29: Photograph of Professor Catherine rskov, credit: rskov
Brosseau JP, Liao CP, Wang Y, Ramani V, Vandergriff T, Lee M, et al
TB-500 is based on a part of TB4, so it should, in theory, have a similar safety profile, but studies specifically analyzing its safety still need to be conducted
53 Mc Cormack et al demonstrated that EA affected the cell cycle progression of T-HESCs by arresting the cell cycle in the G2/M phase
Soluble macromolecules such as amino acids and monosaccharides up to 1,400 Da in size are able to readily cross this membrane via a channel that is permeable to both cations and anions ( The PVM in the related apicomplexan parasite, Toxoplasma gondii , has a similar exclusion limit for macromolecules to that of Plasmodium (Schwab et al., 1994), suggesting that related channels may exist to transport soluble macromolecules across their respective PVMs