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This may lead to new vascular targeting strategies aimed at tailoring vessel function to optimize drug response

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Cancer Res 72(2):402407 Shrimali RK et al (2010) Antiangiogenic agents can increase lymphocyte infiltration into tumor and enhance the effectiveness of adoptive immunotherapy of cancer

However, the drug falls into an exceptional category, in that, it can be taken orally, exhibits very few side-effects, and appears to have lasting effects which persist even after the cessation of treatment