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[PubMed: 8359644] 166

Evidence of central inflammation in fibromyalgia-increased cerebrospinal fluid interleukin-8 levels

This may be relevant with low dietary creatine, vegetarian or vegan diets, rapid growth, high muscle demand, athletic activity or increased brain-energy needs

Endotext 2024

Additionally, PCs provide effective protection against cerebral ischemia-reperfusion injury by alleviating oxidative stress, promoting angiogenesis, and activating antioxidant enzyme pathways