Therefore, EBV may be involved in the brain-gut-microbiota axis communication in MS through various mechanisms, including affecting gut microbiota composition and metabolites, inducing an inflammatory microenvironment in the gut, damaging the intestinal barrier and influencing the phenotypes of immune cells in the gut and CNS by cooperating and antagonizing with the bacteria
"This makes psychiatrists like me interested in what else activation of these receptors can do, and one of the main areas of interest is motivation." Mansur called motivation a "key clinical problem in depression, which is not only feeling low and sad, its as much about losing motivation and interest in things." Existing treatments for depression do not address that combination, he said
Shared Southern European Trends In both Spain and Italy: Public healthcare is still very cautious about paying for GLP-1 medicines for weight loss The private market is growing fast more patients are choosing to pay privately More private clinics are now offering full weight management programmes that combine GLP-1 treatment with nutrition advice and psychological support Supply shortages for Wegovy have been reported in both countries
These medications work through entirely different biological mechanismsone targeting metabolic and gastrointestinal function, the other affecting neuromuscular transmission
It is a licensed prescription medication regulated by the MHRA
Adjusting the dose and monitoring progress helps ensure the treatment is effective