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3.5 Apoptosis regulation 3.5.1 Apoptosis promotion Ultraviolet radiation disrupts epidermal homeostasis by concurrently activating pro-apoptotic pathways (e.g., p53/Bax upregulation, p38 MAPK activation) and pro-survival signals (e.g., COX-2-mediated proliferation) (Mlitz et al., 2016

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