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Clinical trials examining GHK-Cu effects on facial hyperpigmentation have reported variable results, with some studies documenting 15-30% reductions in melanin index measurements over 8-12 week treatment periods, while others report minimal pigment-lightening effects

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[DOI] [Google Scholar] 150.Pugliese M., Biondi V., Merola G., Landi A., Passantino A

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Since most ampoules only have low concentrations of plant extracts, theres very little side effects