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G.ChangT

(86) showed that castration of male rats lowered the levels of CAT, SOD, GPx, and GR in the left ventricle of the heart, as well as GSH and protein-thiol groups, and increased lipid peroxidation and nitrotyrosine concentrations

J.PurvisT

It's like, Why

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However, if the ATP-depleting futile 5-oxoproline cycle becomes activated, this may also contribute to the hepatic and renal ATP and energy depletion