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This study shows that protofibrillar -synuclein can permeabilize vesicles, allowing the leakage of small molecules, such as dopamine, which could potentially lead to an increase in cytoplasmic dopamine levels

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Several studies report that plasma glutathione levels decrease with age, thus increasing the chances of developing chronic health conditions.

doi: 10.1192/bja.2024.74

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I often explain this the way a mechanic uses different diagnostic tools