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Lal H, Ahmad F, Woodgett J, Force T

[DOI] [PMC free article] [PubMed] [Google Scholar] 94.Linnebjerg H., Park S., Kothare P.A., et al

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This structural change compromises the medication's ability to bind effectively to GLP-1 receptors, potentially reducing therapeutic efficacy

The nuclear factor erythroid 2-related factor 2 ( NFE2L2 or NRF2) transcription factor is constitutively activated in many cancers and promotes a specific gene expression program involved in cellular detoxification, redox buffering, and metabolic rewiring (Cancer Genome Atlas Research, 2012