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Additionally, upregulation of lipid peroxidation and inflammatory responses in retinal vascular ECs prompt EC dysfunction and increase permeability (18)

Crocin and Crocetin Crocin and crocetin are both carotenoid chemical compounds of Crocus sativus L

For example, therapy may work by enhancing CREB/BDNF signaling, increasing hippocampal mRNA level of Glt-1 , thereby preventing neuronal apoptosis and reducing oxidative stress, as shown in the case of memantine treatment [51]

doi: 10.1371/journal.pone.0064401

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It is a glucagon-like peptide-1 (GLP-1) receptor agonist, which means it mimics the action of the naturally occurring hormone GLP-1 in the body