Journal of Cell Biology , 166 (2), 157159
Clinical evidenceparticularly for -lipoic acid, curcumin, green tea, vitamin B12, melatonin, and CoQ10supports symptomatic relief and functional improvement, although trials remain small and heterogeneous
It also prevents and treats symptoms associated with Vitamin B12 deficiency, including skin and coat problems, anemia, loss of appetite, weight loss, weakness, and lethargy
It also raised levels of Th1-associated cytokines such as IFN-, IL-2, and TNF- and enhanced the growth of the CD8 + dendritic cell (DC), which exhibited higher expression of CD86 and CD80 molecules [101]
10.3390/molecules26082347 80 FissehaN.HammesoW
IV injections offer fast delivery, often used under clinical supervision