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Recent mathematical modeling and small-scale observations have looked at what happens when the dosing interval is stretched
P.Flor-GarcaM.Terreros-RoncalJ.RbanoA.CafiniF.Pallas-BazarraN.et al (2019)
Metformin and Autophagy Autophagy is a process necessary for the removal of damaged proteins and organelles and plays an important role in the regulation of cell aging, providing a supply of nutrients to maintain cellular function during starvation, and inhibition of autophagy mimics accelerated aging (228, 229)
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The growing burden of chronic metabolic disorders worldwide, combined with increasing healthcare expenditures and stronger clinical emphasis on long-term weight management and glycemic control, is compelling healthcare providers, payers, and patients to adopt advanced GLP-1 agonist therapies