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Dehydration can lead to muscle cramps and weakness, including in the lower back

It enhances metabolic function by: Accelerating fat breakdown Improving insulin sensitivity Enhancing nutrient partitioning Boosting overall metabolic rate This combination creates an environment conducive to reducing body fat while preserving lean muscle tissue - a crucial benefit for those struggling with hormone-related weight management issues

2018;141:e35766

First of all, again, why are they using the trial in which weight was a secondary endpoint, rather than the trial where it was the primary endpoint

Is There a Preferred Time of the Day to Use FRC

Participants were given 120 mg of Orlistat and placed on a calorie-restricted diet (600kcal/day deficit) for 52 weeks