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After a 5-hour fast, mice were administered water or sitagliptin at 14 g/mouse (gut-selective dose) or 10 mg/kg (systemic DPP-4 inhibition) by gavage

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At the same time, average total payments per patient which included out-of-pocket costs as well as payments from private insurers, employers and government programs increased 157% for adults without diabetes and 36% for those with diabetes

The semaglutide escalation typically completes in 16-20 weeks