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This resulted in appetite suppression and weight loss in the murine models employed in the research

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In addition, it can have harmful side effects including hives, difficulty breathing/ swallowing, numbness, tingling, weakness, painful or difficult urination, blood in the urine, bone pain, testicular pain and osteoporosis

Togawa, "Diurnal Variation of Cadmium-induced Mortality in Mice", J

Recent methodological advancesincluding organotypic slice cultures, three-dimensional brain organoids and in vivo imaging approachesoffer scalable and physiologically relevant platforms that more faithfully capture astrocyte heterogeneity and functional consequences

Studies indicate KLF9 as a key feedforward regulator of response to glucocorticoid activity (Gans et al., 2020), consistent with it being a glucocorticoid-induced gene (Bonett et al., 2009)