Yes, there are specific circumstances where you should not add L-Glutathione or NAD+ to your wellness routine
Each addresses a layer of skin biology the others cannot reach
One study covered in the review found that a topical containing Syn-Ake resulted in a 52% reduction in wrinkle size after 28 days of use.34 (As an interesting side note, you may have noticed that Syn-Ake kind of looks or sounds like the word snake. This is because the synthetic peptide Syn-Ake is an analog of a natural one called Waglerin-1, which is derived from the venom of the Southeast Asian temple viper.)34 As with Allies of Skin, much of the research behind the ingredients in The Ordinarys product is positive
Curcumin Reported dosage: 24.5 grams daily (but formulations vary) Curcumin is a major active constituent of turmeric, a rhizome used for millennia as a traditional culinary ingredient and in Ayurvedic medicine as a remedy for health concerns such as musculoskeletal, digestive, and skin conditions (Aggarwal 2007)
The thiol group of glutathione chelates copper ions on the active site of enzyme tyrosinase thus inhibiting it
Discuss with your PlexusDx team whether B12 supplementation makes sense for your baseline health status and treatment timeline