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Approximately 322 adult patients with bronchiectasis of various etiologies were randomized to receive once-daily placebo or three different doses of BI 1291583 (1 mg, 2.5 mg, or 5 mg) in a 2:1:1:2 allocation ratio

Together, these findings suggest that mitochondrial metabolism can dictate response to 5FU

Darius Zagunis, M.D., providing expert care

A selective dual inhibitor of the PDE3 and PDE4 enzymes, Ohtuvayre produces both bronchodilator and non-steroidal anti-inflammatory effects

doi: 10.1002/cncr.33587

Specifically, among treatment agent, Schisandrin C demonstrated the largest effect size with concomitant reduction in heterogeneity [SMD = 7.52, 95% CI (10.13, 4.91), I 2 = 0.0%, p = 0.579]