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Canagliflozin ameliorated myocardial remodeling in HFpEF rats by optimizing cardiac energy metabolism, enhancing mitochondrial function, and consequently reducing myocardial hypertrophy and fibrosis, with simultaneous improvement of diastolic function [115]

Research backs this up: when using GLP-1s to aid in weight loss, they were found to effectively reduce BMI, triglycerides, waist circumference, and total testosterone in people with PCOS, according to a 2024 meta-analysis in the Journal of Diabetes and its Complications

Due to possible side effects like nausea and diarrhea, microdosing GLP-1s has become popular

Your diet may make an impact on the amount of elastin and collagen in your skin

Massachusetts BCBS Massachusetts was among the most vocal about its decision