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Despite the ever-growing list of FDA-approved drugs, the success of anti-angiogenic therapy has so far been quite limited, only providing short-term relief from tumor growth before resistance occurs and typically resulting in modest survival benefits

FGP is currently funded by research awards from the NINDS of National Institute of Health

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The relative expression levels of each gene were quantitated using the 2 CT method and normalized to the amount of endogenous glyceraldehyde-3-phosphate dehydrogenase (GAPDH)

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Cell debris was removed by centrifugation at 4,400 g at 4 C for 30 min, and the clarified cell lysate was directly used for biocatalytic reactions