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Most studies (25) were retrospective single-center studies, 4 were multicenter studies, and 6 used large databases

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Cardiovasc.Drugs Ther 2005;19(4):267-275

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However, with early diagnosis and initiation of therapy the average duration of episodes can be brought down to 4.1 to 0.8 days and the number of emergency room visits from 2.3 to 0.6 times per year [5]

2 H-NMR spectra were obtained with the 2 H loop and a single-pulse sequence, using saturation bands to suppress signals from tissues other than the brain