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Furthermore, activated JNK translocates the mitochondria, and recruits cytoplasmic Bax, which triggers the opening of MPTP, thereby leading to the loss of membrane potential and the depletion of ATP

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doi: 10.3892/ijo.2014.2419

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However, TMZ intervention increased the ejection fraction and fractional shortening, and this phenomenon was not observed in the other groups (Figures 6J, K)