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Risk factors that may prompt additional consideration include: Active gastrointestinal symptoms (nausea, vomiting, abdominal pain) Recent dose increases or being in the dose-escalation phase Higher doses of semaglutide Known gastroparesis or other conditions affecting gastric emptying Obesity with GERD or hiatal hernia Based on the 2024 multi-society guidance, most patients can continue GLP-1 receptor agonists before elective procedures with appropriate risk assessment and mitigation strategies, rather than automatic postponement

Liraglutide reduces vascular damage, neuronal loss, and cognitive impairment in a mixed murine model of alzheimers disease and type 2 diabetes

Noh Y, Yin H, Yu OHY, Bitton A, Azoulay L

Whereas Orforglipron can be taken any time during the day with or without food

Updated May 19, 2026

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