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GLP-1 (Glucagon-Like Peptide-1) is a gut-derived incretin hormone that regulates postprandial insulin secretion and inhibits glucagon release

These medicationsincluding semaglutide (injectable Ozempic, oral Rybelsus, injectable Wegovy), dulaglutide (Trulicity), and liraglutide (Victoza, Saxenda)mimic the action of endogenous GLP-1 while resisting degradation by the enzyme dipeptidyl peptidase-4 (DPP-4)

doi: 10.4103/ijmr.IJMR_1768_17 4 CondonC

Cummings, Department of Biomedical Sciences, Cornell University College of Veterinary Medicine, 930 Campus Road, Ithaca, New York 14853, USA

Identification and localization of glucagon-like peptide-1 and its receptor in the brain