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The apolipoprotein E (APOE) genotype was determined using imputed genotypes of SNPs rs429358 (APOE 4) and rs7412 (APOE 2) 26,27

Richie: Yes, supplementation is an effective way to help maintain optimal levels of GSH in our cells and tissues

Vander Heiden MG, Cantley LC, Thompson CB

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Dot plots show cell viability analyzed by lactate dehydrogenase (LDH) release

In addition, consistent with the findings reported elsewhere, we found DMF induces the activation of NRF2, and NRF2 targets such as those involved in cystine uptake (SLC7A11) and GSH biosynthesis (GCLM and GCLC, the mediator and catalytic subunits of GCL) (Fig