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It should be acknowledged that these studies had several limitations, including the limited accuracy of the technique of 131I scans and the unknown status of receptor expression of the treated TC

Common gastrointestinal side effects include, according to the Saxenda Summary of Product Characteristics (SmPC): Nausea (reported in approximately 40% of patients) Diarrhoea (affecting around 20% of users) Constipation (occurring in approximately 20% of patients) Vomiting (experienced by roughly 16% of users) Dyspepsia (indigestion) Abdominal pain or discomfort Gastro-oesophageal reflux disease (GORD) These effects are typically most pronounced during the initial weeks of treatment and often diminish as the body adjusts to the medication

There was substantial evidence supporting the role of ABC transporters and CYP in ivermectin resistance and detoxification

Potential Market Implications: For Patients: May see increased access and improved affordability

Provide essential fatty acids , including omega-3 fats, that support brain and heart health

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