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Phase 2 trial data published in the New England Journal of Medicine in 2023 showed participants lost up to 24% of body weight over 48 weeks at the highest dose

I was able to lose 25 lbs in 20 weeks and am feeling as amazing as I did before I had three kids

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What It Feels Like to Be on a GLP-1 Everyones experience is different, but heres what most women in the Josie community notice in their first few weeks: You feel full faster meals are more satisfying, and youre not looking for something to munch on an hour later

The latter means that they can react with cellular glutathione, causing its depletion and thus inducing cellular toxicity