[2] [3] The Summary of Product Characteristics (SmPC) approved by the MHRA does not list thrombotic events among the known side effects of tirzepatide
Posted April 23, 2018
Any references to biological effects are based solely on experimental and preclinical data
Stop immediately and contact your doctor if: Severe neck swelling or a palpable thyroid mass develops Symptoms of thyrotoxicosis appear: rapid heartbeat, severe anxiety, excessive sweating, tremor, sudden unexplained weight loss Severe pancreatitis symptoms: intense upper abdominal pain radiating to the back with nausea and vomiting You discover you are pregnant Discuss with your endocrinologist if: TSH levels become unstable despite levothyroxine adjustments New thyroid nodules appear on follow-up ultrasound Hair loss is severe and persistent despite adequate nutrient levels Fatigue worsens despite thyroid levels appearing normal Autoimmune flare frequency appears to increase You reach your target weight and want to explore discontinuation For patients who achieve their weight loss goals and want to stop GLP-1 therapy, tapering is recommended over abrupt discontinuation
Mounjaro interactions Mounjaro can interact with other drugs, so it's important to discuss all other medications you're taking with your provider
Current areas of scientific investigation include multi-receptor metabolic regulation studies, appetite and energy balance pathway research, glucose and insulin signaling investigations, fat oxidation and energy expenditure studies, advanced metabolic pathway analysis, and peptide-receptor interaction research
