Ferroptosis: mechanisms, biology and role in disease
This observation was further validated by flow cytometry (Fig
Indeed, patients who were originally described as suffering from deficiencies in the LCAD enzyme were, in fact, found to be harboring pathogenic variants in the ACADVL gene which encodes the VLCAD enzyme
Wang H, Zhang Y, Wu X, Wang Y, Cui H, Li X, et al
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Specifically, in a prospective cohort study, l-carnitine was associated with higher risk of prevalent coronary artery disease, peripheral artery disease, and overall CVD, possibly mediated by its intestinal metabolite, TMAO [5]