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The effective concentration in cellular assays is 10 to 100 nM, with loss of efficacy at higher concentrations

translating to 4-5% reduction from baseline

GLP-1 RAs mimic the action of the endogenous incretin hormone GLP-1 by activating GLP-1 receptors in pancreatic -cells

The high purity and well-balanced concentration ensure it integrates seamlessly into experimental protocols

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(5) EFFET Trial (France): Lower dose (5 mg twice daily for 12 weeks) improved autism severity scores, especially communication