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In the gastrointestinal tract, COX-1-derived prostaglandins function to increase production of the thick mucus/bicarbonate layer that coats gastric surfaces and buffers them against stomach acid (Vonkeman 2010)
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It appears to bind to p53 and thereby may prevent apoptotic death of the senescent cells
RcGST1 interacts with all the highly weighted GST members in the network, and the three DHAR subfamily members who directly interact with it are the three most important cores in the network