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Although neuroprotective medicine has been efficacious in a preclinical setting, patient response rates at the clinical level vary, and only a small subset of the patients within a large cohort respond favorably to these treatments leading to a lack of statistically significant clinical outcomes [181]

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Unlike many peptides that require injection or intranasal delivery, GSB-106 has demonstrated efficacy through oral administration in animal models

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The side chains of W222 and I131 rotate 180 and 90, respectively, compared with the 1EEM structure due to the binding of the C1-27 chloride atom