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This study provides important information by demonstrating, both in vitro and in vivo in mice, that lipotoxicity alters incretin signalling via reductions in receptor levels

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This is not a failure of willpower but rather a predictable biological response to the removal of pharmacological intervention

Bautista JL, Yu S, Tian L

For the full trial picture on how much weight each GLP-1 produces and how fast, see our dedicated guide

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